Curcumin-meropenem synergy in carbapenem resistant Klebsiella pneumoniae curcumin-meropenem synergy
نویسندگان
چکیده
منابع مشابه
Three Dimensional Checkerboard Synergy Analysis of Colistin, Meropenem, Tigecycline against Multidrug-Resistant Clinical Klebsiella pneumonia Isolates
The spread of carbapenem-non-susceptible Klebsiella pneumoniae strains bearing different resistance determinants is a rising problem worldwide. Especially infections with KPC (Klebsiella pneumoniae carbapenemase) - producers are associated with high mortality rates due to limited treatment options. Recent clinical studies of KPC-blood stream infections revealed that colistin-based combination t...
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Klebsiella pneumoniae showing high resistance to all β-lactams except imipenem, designated as ISMRK (imipenem-susceptible meropenem-resistant Klebsiella) is emerging in Japan. The carbapenem resistance of ISMRK cannot be screened by the Vitek and the RAISUS rapid automated susceptibility test systems, which may lead to inappropriate antimicrobial therapy, resulting in compromised patient outcomes.
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Objective: Burn wound infection is a severe complication of thermal injury. Patients with severe burn injuries need urgent care to diminish complications after severe burns. Wound infections are commonly considered one of the most serious burn complications, particularly those that are caused by extensively drug-resistant (XDR) bacteria with few therapeutic choices. The objective of this study ...
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Shizuo Kayama, D.D.S., Norifumi Shigemoto, M.D., Ryuichi Kuwahara, M.S., Takashi Ishino, M.D., Kentaro Imon, M.D., Makoto Onodera, B.S.E., Michiya Yokozaki, M.D., Hiroki Ohge, M.D., and Motoyuki Sugai, D.D.S. Project Research Center for Nosocomial Infectious Diseases, Hiroshima University; Department of Bacteriology, Hiroshima University Graduate School of Biomedical & Health Sciences; Departme...
متن کاملLimiting and controlling carbapenem-resistant Klebsiella pneumoniae
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is resistant to almost all antimicrobial agents, is associated with substantial morbidity and mortality, and poses a serious threat to public health. The ongoing worldwide spread of this pathogen emphasizes the need for immediate intervention. This article reviews the global spread and risk factors for CRKP colonization/infection, and provides a...
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ژورنال
عنوان ژورنال: Iranian Journal of Microbiology
سال: 2021
ISSN: 2008-4447,2008-3289
DOI: 10.18502/ijm.v13i3.6397